abstract：:To date, there is no biological test available with enough confidence to make alone a diagnosis of Multiple Sclerosis (MS). MS diagnosis criteria are then an association of clinical and para clinical criteria that allow an objective demonstration of dissemination of lesions in both time and space. Adapted MRI criteria...

journal_title：Revue neurologique

authors： Dupel-Pottier C

更新日期：2001-09-01 00:00:00

abstract：:The onset of Multiple Sclerosis usually concerns young adults who are making plans for their life. The personal, familial, professional plans must be adapted to the course of the disease. This adapted daily life must be as normal as possible to prevent the social loneliness which is the principal complication of Multi...

journal_title：Revue neurologique

authors： Moreau T

更新日期：2001-09-01 00:00:00

abstract：:Tremor and movement disorders in multiple sclerosis (MS) patients cause a severe functional impairment. The different types of tremor observed in MS are: cerebellor tremor with a dominant intention component, Holmes tremor characterized by the addition of rest and postural components and palatal tremor. When no medica...

journal_title：Revue neurologique

authors： Viallet F,Witjas T,Gayraud D,Pelletier J,Regis J

更新日期：2001-09-01 00:00:00

abstract：:The indication for a long-term treatment in secondary or primary progressive multiple sclerosis is raised in more than half of the patients with MS. The fact that the pathogenic mechanisms involved in these two entities are unknown makes it difficult to predict the clinical course. The still insufficient knowledge of ...

journal_title：Revue neurologique

authors： Rumbach L

更新日期：2001-09-01 00:00:00

abstract：:The disappearance of autopsies is of concern in Neurology for three reasons: in some cases, such as degenerative diseases, the predictive value of clinical diagnosis is still poor; autopsy is, for Neurology, an important piece of the public health watch; the modern post-genomic research needs tissue samples that canno...

journal_title：Revue neurologique

authors： Hauw JJ

更新日期：2001-07-01 00:00:00

abstract：:Two cases of acute presentation of cervical syringomyelia associated with Chiari malformation are reported. In the first case, dysphagia was the main symptom; the second patient had symptoms suggesting acute brain stem ischemia. The mechanism of this acute onset of the illness is discussed. ...

journal_title：Revue neurologique

authors： Delpirou C,Héroum C,Blard JM,Pagès M

更新日期：2001-07-01 00:00:00

abstract：:Long term L-Dopa medication mainly induces two complications in Parkinson's Disease (PD) patients, i.e. motor fluctuations and dyskinesias. Both of these complications can significantly impair the patient's quality of life. At a high degree of severity, dyskinesias can interfere with everyday tasks, balance, speech, e...

journal_title：Revue neurologique

authors： Maurel F,Lilliu H,Le Pen C

更新日期：2001-05-01 00:00:00

abstract：:This review is devoted to the relationships between phenotype and genotype of the autosomal dominant forms of Alzheimer's disease caused by mutations of presenilins (PSs) and amyloid precursor protein (APP) genes. A first part examines the clinical characteristics mainly the early age of onset and argues about the div...

journal_title：Revue neurologique

authors： Hannequin D,Campion D

更新日期：2001-04-01 00:00:00

abstract：:A 44-year-old woman demonstrated a musical hallucinosis four months after a massive infarction in the territory of the right middle cerebral artery. This musical hallucinosis consisting of familiar tunes, was continuous and perceived by both ears. Magnetic Resonance Imaging, middle and late auditory evoked potentials ...

journal_title：Revue neurologique

authors： Augustin J,Guegan-Massardier E,Levillain D,Lemarchand M,Mihout B,Hannequin D

更新日期：2001-03-01 00:00:00

abstract：:Downward herniation of the cerebellar tonsils through the foramen magnum (Chiari I malformation) is usually revealed by head and neck pain, often associated with brain-stem or spinal cord disturbances. Syncopes are rarely reported and may be difficult to link to their cause when they occur alone. We report two cases w...

journal_title：Revue neurologique

authors： Guillon B,Trochu JN,Olindo S,Desal H,Martin S,Ménégalli D,Fève JR

更新日期：2001-01-01 00:00:00

abstract：:Nineteen patients were found to harbor the mitochondrial DNA A3243G mutation associated with MELAS syndrome (Mitochondrial myopathy, Encephalopathy, Lactic Acidosis and Stroke-like episodes). Eight of them had presented with stroke-like episodes and therefore had a clinical diagnosis of MELAS syndrome. The other 11 pa...

journal_title：Revue neurologique

authors： Laforêt P,Ziegler F,Sternberg D,Rouche A,Frachon P,Fardeau M,Eymard B,Lombès A

更新日期：2000-12-01 00:00:00

abstract：:Finger-to-nose test, fine finger movements, to maintain arms against gravity, alternate movements of hands, Barany's test, muscle tone evaluation, Stewart-Holmes test and handwriting are the conventional clinical tests most frequently used in daily practice to evaluate voluntary movements of the upper limb. We describ...

journal_title：Revue neurologique

authors： Legros B,Jacquy J,Manto MU

更新日期：2000-11-01 00:00:00

abstract：:Spinal neurosarcoidosis is rare (0.43 p. 100 of all sarcoidosis) and can be the initial manifestation of the disease. A 43-year-old right handed African man developed a progressive dorsal neck pain, slowly worsened paresthesia weakness in the legs and a gait disturbance. Magnetic resonance imaging (MRI) scan of the ce...

journal_title：Revue neurologique

authors： Cacoub P,Sbaï A,Hausfater P,Dormont D,Capelle L,Fohanno D,Piette JC

更新日期：2000-10-01 00:00:00

abstract：:We present here recent insight into idiopathic epilepsies and febrile convulsions. For each case, main clinical features are presented, concomitantly with genetic advances (transmission, penetrance and expressivity, locus, gene, gene function, identified mutations). ...

journal_title：Revue neurologique

authors： Moulard B,Crespel A,Malafosse A,Baldy-Moulinier M

更新日期：2000-10-01 00:00:00

abstract：:Normal aging, as well as most of the degenerative diseases of the central nervous system characterizing old age, have an impact on cognitive abilities which are obvious as well as increasingly understood. Cognitive changes in normal ageing realize a plurality of possible patterns of cognitive disabilities. Dementias a...

journal_title：Revue neurologique

authors： Joanette Y,Belleville S,Gely-Nargeot M,Ska B,Valdois S

更新日期：2000-09-01 00:00:00

abstract：UNLABELLED:The primary objective of this prospective, open, non controlled, multicenter study was to collect data on migraine patients' health related quality of life before and after treatment of their migraine attacks by sumatriptan nasal spray 20 mg over a 12 week period. The impact on health related quality of life...

journal_title：Revue neurologique

authors： Géraud G,Valette C

更新日期：2000-07-01 00:00:00

abstract：:We report a case of a western African man, residing in France for 4 years, who developed human African trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense. Diagnosis was made at a late stage of the disease. The disease was misdiagnosed and untreated for several years because the clinical presentation was limi...

journal_title：Revue neurologique

authors： Bédat-Millet AL,Charpentier S,Monge-Strauss MF,Woimant F

更新日期：2000-05-01 00:00:00

abstract：:We report two cases of brainstem tuberculomas with favorable outcome after medical treatment alone. Tuberculomas should be suspected in all cases presenting space-occupying lesions of the brainstem. ...

journal_title：Revue neurologique

authors： Akhaddar A,Bourazza A,El Mostarchid B,Rouimi A,Boutaleb N,Ouahabi H,Mosseddaq R

更新日期：2000-04-01 00:00:00

abstract：:The study of pain integration, in vivo, within the human brain has been largely improved by the functional neuro-imaging techniques available for about 10 years. Positron Emission Tomography (PET), complemented by laser evoked potentials (LEP) and functional Magnetic Resonance Imaging (fMRI) can nowadays generate maps...

journal_title：Revue neurologique

authors： Laurent B,Peyron R,Garcia Larrea L,Mauguière F

更新日期：2000-04-01 00:00:00

abstract：:Neurons, within the nervous system, are organized in different neural networks through synaptic connections. Two fundamental components are dynamically interacting in these functional units. The first one are the neurons themselves, and far from being simple action potential generators, they are capable of complex ele...

journal_title：Revue neurologique

authors： Le Masson G

更新日期：2000-02-01 00:00:00

abstract：:A 30-year-old Vietnamese man experienced severe weakness of four limbs revealing hypokalaemia. Tachycardia and goiter allowed to diagnose a Graves' disease. Thyrotoxic hypokaliemic periodic paralysis is a rare complication of hyperthyroidism in western populations. Electromyogram performed after resolution of the para...

journal_title：Revue neurologique

authors： Navarro V,Fournier E,Girard S,Delattre JY,Eymard B

更新日期：2000-01-01 00:00:00

abstract：:Cluster Headache associates a severe pain generally unilateral and autonomic symptoms with a remarkable periodicity. In the first part we tried to explain the conception of physiopathology of these short lasting headache syndromes and in the second part we described the clinical features. The short lasting primary hea...

journal_title：Revue neurologique

authors： Valade D,El Amrani M

更新日期：2000-01-01 00:00:00

abstract：:As long as motor disorders are controlled by DOPAtherapy, exercise programs and rehabilitation would not appear to be essential for patients suffering from Parkinson's disease. Such measures do become necessary however when secondary occurrence of motor decline develops. Physical medicine and rehabilitation have not b...

journal_title：Revue neurologique

authors： Pélissier J,Pérennou D

更新日期：2000-01-01 00:00:00

abstract：:Rating scales in Parkinson's disease (PD) are generally reliable but are not widely used in practice. UPDRS is the core assessment of PD, its metrologic properties are well known, and it is simple to use after training. However, cognitive and psychic disorders need complementary approaches. For example, MATTIS seems t...

journal_title：Revue neurologique

authors： Tison F

更新日期：2000-01-01 00:00:00

abstract：:We report 5 girls presenting Rett syndrome. All of them were from south Tunisia. They fulfilled the Rett syndrome diagnosis criteria (The Rett syndrome diagnosis criteria work group, 1988). Pregnancy, birth and psychomotor development during the first year of live were normal. The mean age at the onset was 19.8 +/- 2....

journal_title：Revue neurologique

authors： Triki C,Mhiri C

更新日期：1999-11-01 00:00:00

abstract：:The historical role of the French Neurology in the development of anatomo-clinical method is likely to explain why the first communications on electrophysiology were presented in Paris with some delay, as compared with other european societies where the neurophysiological tradition had been more lively. Though clinica...

journal_title：Revue neurologique

authors： Mauguière F

更新日期：1999-10-01 00:00:00

abstract：:Etiological investigations of mental deficiencies and their syndromic analysis have greatly progressed with advancing knowledge in the field of genetics and the advent of new technical procedures. Fast diagnostic tests are now available for certain syndromes, particularly those related to micordeletions. Clinical diag...

journal_title：Revue neurologique

authors： Livet MO,Moncla A,Philip N,Chabrol B,Mancini J

更新日期：1999-09-01 00:00:00

abstract：:Benign neonatal familial convulsions have been recognized as a distinctive epileptic syndrome since 1964. This rare epileptic syndrome was classified in the category of idiopathic generalized epilepsies. Recently, mutations of potassium channel genes (KCNQ2, KCNQ3) were identified as responsible for this autosomic dom...

journal_title：Revue neurologique

authors： Hirsch E,de Saint-Martin A,Marescaux C

更新日期：1999-07-01 00:00:00

abstract：:We report the behavioral symptoms presented by a 57-year-old man as the first sign of a Marchiafava-Bignami syndrome and by a 44-year-old woman with centro and extrapontine myelinolysis. These observations define a clinical entity, that we named callosal dementia characterized by: 5) fronto-limbic signs with coarse in...

journal_title：Revue neurologique

authors： Ghika-Schmid F,Ghika J,Assal G,Bogousslavsky J

更新日期：1999-05-01 00:00:00

abstract：:It is now well established that only clinical trials performed before drug approval are not sufficient for a full modern pharmacological evaluation of drugs and treatments. The need of both pharmacovigilance and pharmacoepidemiology is underlined in order to evaluate drugs under real conditions. After a summary of met...

journal_title：Revue neurologique

authors： Montastruc JL,Bagheri H,Lapeyre-Mestre M,Senard JM

更新日期：1999-04-01 00:00:00

abstract：:Ataxic hemiparesis is a syndrome in which pyramidal and cerebellar signs occur on the same side. Few authors have suggested that signs or symptoms can orientate toward a supratentorial or toward an infratentorial lesion. We have studied the risk factors and the clinical symptoms of 61 patients consecutively admitted f...

journal_title：Revue neurologique

authors： Besson G,Vincent E,Hommel M,Perret J

更新日期：1999-03-01 00:00:00

abstract：:Listeria neuromeningitis presents as febrile rhombencephalitis in half the patients, often with persistent sequelae such as cranial nerve palsy. We report the case of a man who developed central apnea with simultaneous consciousness impairment subsequent to an infectious disease. Magnetic resonance imaging showed low ...

journal_title：Revue neurologique

authors： Milhaud D,Bernardin G,Roger PM,Magnié M,Mattei M

更新日期：1999-02-01 00:00:00

abstract：:This article presents critical aspects of the pivotal phase III study that led to approval of interferon beta-1a (Avonex) as treatment for relapsing-remitting multiple sclerosis (MS). An update on data from the pivotal study or other open studies, further demonstrating the practical clinical impact of Avonex, are also...

journal_title：Revue neurologique

authors： Vermersch P

更新日期：1999-01-01 00:00:00

abstract：:Cortical heterotopia is defined as the misplacement of a group of neurons displaced to a precise localization in the neocortex and results from perturbed migration along the glial guide, either because of glial destruction or molecular anomalies. Heterotopic neurons are rarely dispersed but are rather grouped in nodul...

journal_title：Revue neurologique

authors： Chevassus-au-Louis N,Robain O

更新日期：1999-01-01 00:00:00

abstract：:Arterial hypertension is the leading risk factor for all stroke subtypes. However, its relationship with cognitive decline and dementia is more complex than a simple causal relationship. Cognitive functions are worse in patients with arterial hypertension, especially when the level of education is lower, age higher an...

journal_title：Revue neurologique

authors： Leys D,Pasquier F

更新日期：1999-01-01 00:00:00

abstract：:Besides the optimal management of risk factors for stroke and carotid surgery, antiplatelet agents are the cornerstone for prevention of cerebral ischaemia. The aim of this overview is to determine their role in the prevention of cerebral ischaemia, from available literature. In primary prevention, the benefit of aspi...

journal_title：Revue neurologique

authors： Leys D

更新日期：1999-01-01 00:00:00

abstract：:In this article the pathophysiology of cerebral ischemia is reviewed. The concept of penumbra is explained, and a distinction is made between ischemic necrosis, which occurs in the severely ischemic regions and is associated with loss of calcium and glutamate homeostasis, and programmed cell death, or apoptosis, which...

journal_title：Revue neurologique

authors： Hakim A

更新日期：1999-01-01 00:00:00

abstract：:This decade witnessed a resurgence of interest in vascular dementia (VaD) as an increasingly important cause of senile dementia. Although definitions of dementia in general, and of VaD in particular, are still controversial recent diagnostic criteria for VaD acknowledge that pathogenetic mechanisms different from mult...

journal_title：Revue neurologique

authors： Román GC

更新日期：1999-01-01 00:00:00

abstract：:Three cases of extracranial vertebral artery dissections with upper limb peripheral motor deficit (C5-C6) are reported. Six similar cases were also found in the literature. Central neurological symptoms occurred in five of these nine cases, suggesting the diagnosis of dissection. The peripheral motor or sensorial defi...

journal_title：Revue neurologique

authors： de Bray JM,Penisson-Besnier I,Giroud M,Klein J,Tanguy JY,Pasco A,Dubas F

更新日期：1998-11-01 00:00:00

abstract：:We report a biopsy proven case of cerebral giant cell angiitis associated with cerebral amyloid angiopathy. Clinical history and radiological lesions were rapidly progressive. The patient recovered with corticosteroid treatment. The pathogenesis relationship between angiitis and amyloid angiopathy are discussed. ...

journal_title：Revue neurologique

authors： Masson C,Hénin D,Colombani JM,Dehen H

更新日期：1998-10-01 00:00:00